Feeling run down? A little ‘young blood’ might fix you right up

Dr. Amy Wagers. (The rumor that Wagers is actually 62 years old has not, repeat not, been substantiated.)

Dr. Amy Wagers. (The rumor that Wagers is actually 62 years old has not, repeat not, been substantiated.)

It sounds like something out of a bad movie. But Amy Wagers and other researchers at the Harvard Stem Cell Institute and Joslin Diabetes Center in Boston have found a way to reverse signs of aging in older mice.

“They recovered functions not quite to ‘young’ levels but really quite significantly, and easily, easily distinguishable from older animals that didn’t see this ‘young blood’ within their tissues,” Wagers said.

From Technology Review:

In the experiment, Wagers and team surgically connected the circulatory systems of two mice, allowing older animals to be exposed to blood–and all the molecules and cells it carries– from young animals. They found that the procedure made the blood-forming stem cells in older animals act young again; the overall number of these cells decreased, and the cells generated different varieties of blood cells in more appropriate ratios. “In aged animals, many of the changes we see normally that are associated with age were reversed,” said Wagers.

131 comments Add your comment

I Report (-: You Whine )-: mmm, mmmm, mmmmm!

January 30th, 2010
10:43 am

Great, all we need now is to find some youngun we can attach to.

eewww

Doesn’t it figure this excites the liberals, killers of the innocent?

I Report (-: You Whine )-: mmm, mmmm, mmmmm!

January 30th, 2010
10:45 am

Nasty Pelosi would make the perfect test case, maybe even awaken her long dead brain functions along with her youthful vitality, I suggest we immediately sew one of the obozo children to her.

Then she’d be half black too, bonus points.

I Report (-: You Whine )-: mmm, mmmm, mmmmm!

January 30th, 2010
10:47 am

I didn’t raise this gruesome subject, just sayin….

TnGelding

January 30th, 2010
10:47 am

I could sure use some! Recently discovered something that sees to be helping a little tho:

http://www.wellesse.com/productdetail.asp?id=1

Much better than the pills I had been taking.

Jay

January 30th, 2010
10:47 am

That’s some mind you got there, Reporter.

TnGelding

January 30th, 2010
10:48 am

RLJ

January 30th, 2010
10:57 am

Didn’t someone try this experiment a few centuries back in Transylvania?

joan

January 30th, 2010
11:01 am

That is a scary concept. And why exactly would anyone want to live too long? There is no way you will want to work for 90 years, because if you retire earlier, you will certainly run out of money to live on. Seems like we are living a lot longer than most people plan for right now, so maybe we ought just to let the mortality rate drop a little, and we can all have a better chance of living decently to a reasonable age, rather than living on welfare (and poorly) to an old age.

TaxPayer

January 30th, 2010
11:09 am

Such studies have been rendered moot with the advent of Cylon technology.

@@

January 30th, 2010
11:10 am

Weird! Human leeches?

Let me think this thru….leftists think the aged are a drain on society. They also advocate a woman’s right to choose abortion. Will the unborn now have value?

Will they continue to support “sucking ‘em out” or will they now go for “sucking from them”?

I agree with Andy.

ewwwww

I Report :-) You Whine :-( mmm, mmmm, mmmmm!

January 30th, 2010
11:15 am

Why does Bookman’s comment about my massively unfair advantage keep jumping around?

Bruno

January 30th, 2010
11:17 am

“That is a scary concept. And why exactly would anyone want to live too long?”

I’m with you, joan. I don’t think we’re meant to last forever.

http://www.youtube.com/watch?v=Y3Ufx7SmZ5E

Normal

January 30th, 2010
11:29 am

“That is a scary concept. And why exactly would anyone want to live too long?”

Still, I’ll take a case…

Normal

January 30th, 2010
11:30 am

In case we are doing Saturday at the movies today, I want to put out an early one. Anybody ever see the movie, “Neverwas”. It was not given great reviews and was never released, but I watched it on cable and ordered it right after the movie ended. Try it.,..

Cut the debt

January 30th, 2010
11:41 am

The older mouse would have an enormous svanztooker.

He’ll be quite popular.

Jay

January 30th, 2010
11:42 am

“Ahhh, sweet mystery of life, at last I’ve found you….”

@@

January 30th, 2010
11:43 am

Normal:

You and jay wouldn’t happen to be members of The Sanguinarian Community, would ‘ya?

Symptoms of blood deprivation, according to Sanguinarians, include extreme fatigue, autoimmune deficiencies, headaches, frequent illness, muscle and joint pain, emotional distress, uncontrollable rages, and other problems that cannot be traced to any known disease. Some Sanguinarians report that they suffered for years with such symptoms and achieved almost instant relief when they began drinking blood.

Sanguinarians are modern day vampires.

Normal

January 30th, 2010
11:47 am

DoggoneGA

January 30th, 2010
11:47 am

I’d like to know the effect on the younger mouse

getalife

January 30th, 2010
11:47 am

RW-(the original)

January 30th, 2010
11:48 am

Maybe it’s just luck of the draw from when I hit this page but it’s really creepy to see what has Jay B excited this morning running right beside three ad/stories titled Breakthrough discovery for joint relief, skin cream found that fights cellulite (complete with supposed before and after pictures), & All-natural muscle-building breakthrough uncovered.

Has the AJC become an online depot for crackpot snake oil products?

joe matarotz

January 30th, 2010
11:48 am

Hooking up Pelosi to Tutankhamun’s mummy would be an improvement for her. It won’t do much for old Tut, though.

FrankLeeDarling

January 30th, 2010
11:50 am

Hey did you see Obama rip the GOP without a teleprompter.

Road Scholar

January 30th, 2010
11:56 am

Jay or anyone: Do you have a link to veiw the entire Obama/Repub session from yesterday?

RW-(the original)

January 30th, 2010
11:57 am

Road Scholar

January 30th, 2010
12:00 pm

Poor attempt RW.

I Report (-: You Whine )-: mmm, mmmm, mmmmm!

January 30th, 2010
12:02 pm

Hey did you see Obama rip the GOP without a teleprompter.

We did, in fact-

Fun = stammer, stutter, uh, uh.

I love when he loses his thought pattern. That look of fear on his face is fantastic.

Your little babbling idiot.

http://pajamasmedia.com/richardfernandez/2010/01/29/obama-at-the-gop-retreat/

RW-(the original)

January 30th, 2010
12:04 pm

Speaking of junk science

The chairman of the leading climate change watchdog was informed that claims about melting Himalayan glaciers were false before the Copenhagen summit, The Times has learnt.

Rajendra Pachauri was told that the Intergovernmental Panel on Climate Change assessment that the glaciers would disappear by 2035 was wrong, but he waited two months to correct it. He failed to act despite learning that the claim had been refuted by several leading glaciologists.

The IPCC’s report underpinned the proposals at Copenhagen for drastic cuts in global emissions.

Road Scholar

January 30th, 2010
12:04 pm

Better than being a BIG babbling idiot…

FrankLeeDarling

January 30th, 2010
12:12 pm

hurt a little didn’t it.

ZZZZ

January 30th, 2010
12:17 pm

Hook me up to someone with pizzazz.

Cut the debt

January 30th, 2010
12:19 pm

The mouse would have an extra lifeline on “Who want’s to be a millionaire mouse?”.

FrankLeeDarling

January 30th, 2010
12:22 pm

Redneck Convert (R--and proud of it)

January 30th, 2010
12:29 pm

Well, this is real bad news for all the young people out there. One day you’re strolling around town making babys and taking dope. The next day some old coot’s grabbed you, took all your blood and put his own in you, and you’re begging for Viagra and looking at liver spots. Meanwhile, alot of old folks are coming down with VD and demanding more bike trails and places to run.

Something to think about. Have a good day everybody.

Cut the debt

January 30th, 2010
12:50 pm

Do you think this would work with one-eyed mice?

TaxPayer

January 30th, 2010
12:56 pm

Last year, in a series of “town-hall meetings” across the country, Americans got the chance to debate President Obama’s proposed healthcare reforms.

What happened was an explosion of rage and barely suppressed violence.

Polling evidence suggests that the numbers who think the reforms go too far are nearly matched by those who think they do not go far enough.

But it is striking that the people who most dislike the whole idea of healthcare reform – the ones who think it is socialist, godless, a step on the road to a police state – are often the ones it seems designed to help.

In Texas, where barely two-thirds of the population have full health insurance and over a fifth of all children have no cover at all, opposition to the legislation is currently running at 87%.

Probably just bad blood.

RW-(the original)

January 30th, 2010
1:15 pm

The rest of that BBC piece is mostly just the same leftist hand wringing we’ve heard for years so I understand why a source wasn’tt provided, but they did get close at one point.

They do it because they resent having their interests decided for them by politicians who think they know best.

Scout

January 30th, 2010
1:24 pm

I’m just glad Ted Kennedy is gone before they came up with this !

TaxPayer

January 30th, 2010
1:25 pm

Gore: “Under the governor’s plan, if you kept the same fee for service that you have now under Medicare, your premiums would go up by between 18% and 47%, and that is the study of the Congressional plan that he’s modelled his proposal on by the Medicare actuaries.”

Bush: “Look, this is a man who has great numbers. He talks about numbers. “I’m beginning to think not only did he invent the internet, but he invented the calculator. It’s fuzzy math. It’s trying to scare people in the voting booth.”

Mr Gore was talking sense and Mr Bush nonsense – but Mr Bush won the debate. With statistics, the voters just hear a patronising policy wonk, and switch off.

This is one point where I disagree. It’s not that the use of statistics is off-limits per se with a “conservative”. In this case it was just the lack of a proper analogy that led to Gore’s loss in the debate. If Gore had related his statistics to say ERAs or total yards passed, depending on the season, etc., he would have been a shoe in with this segment of the voting population. If you do not connect with your intended audience, you might as well be talking to a wall.

Scout

January 30th, 2010
1:35 pm

How come the mainstream media never went after Clinton like they did Edwards ?

@@

January 30th, 2010
1:37 pm

They do it because they resent having their interests decided for them by politicians who think they know best.

Funny, RW, when I was revisiting Alinsky’s “Rules for Radicals” it said this:

“‘The organizer’s first job is to create the issues or problems,’ and ‘organizations must be based on many issues.’ The organizer ‘must first rub raw the resentments of the people of the community; fan the latent hostilities of many of the people to the point of overt expression. He must search out controversy and issues, rather than avoid them, for unless there is controversy people are not concerned enough to act.

The problem with Obama’s using that approach, is that he very quickly discovered that most Americans are not the liberal tools he cut his teeth on.

Those who willingly accept the role of victim, are an anomaly in the American psyche overall.

Scout

January 30th, 2010
1:41 pm

Headline: “After NYC balks at hosting trial for 9/11 suspects, Obama administration scrambles for new venues — but where?”

As close to the White House as you can get it ………………

Scout

January 30th, 2010
1:47 pm

Hedline: “MORE RULES: OBAMA TO TAKE ON COLLEGE FOOTBALL”

He’ll look great in that striped shirt with a whistle and a yellow flag to throw.

Hillbilly Deluxe

January 30th, 2010
1:50 pm

As strange as it may sound in todays world, I don’t wanna be younger. I’ve got some gray hair, a few wrinkles, and a whole lot more scars than the average person and I earned every damn one of ‘em.

RW-(the original)

January 30th, 2010
1:52 pm

@@,

Maybe Obama’s psychobabble really means he’s saved or created 2 million issues.

The public isn’t buying it anymore though and that can only be good news for the country.

Scout

January 30th, 2010
1:52 pm

I am pleased that abortion doctor murderer got life in prison and I hope it’s without parole.

I only wish all of his cellmates were abortion doctors.

RW-(the original)

January 30th, 2010
1:54 pm

Is there actually a study somewhere that tells us the average number of scars per person?

Sadly, I bet there is.

@@

January 30th, 2010
2:07 pm

jay, I don’t mean to hurt your feelings, but why do you put up crap like this when Kyle’s running something worthy of discussion?

Do you view government AND Obama as the ONLY solution to the problems that face us?

ROLLERGIRL

January 30th, 2010
2:07 pm

I can picture obama sewing some young mice to his Healthcare bill right about now…

Jay

January 30th, 2010
2:10 pm

Your concern for my feelings is appreciated, @@.

And if Kyle’s place is more suitable to you, I’m glad for you.

ROLLERGIRL

January 30th, 2010
2:10 pm

“Uh Uh Uh , Rahm, uh uh uh bring me the stapler and uh uh the duct tape”

RW-(the original)

January 30th, 2010
2:19 pm

Anybody find it a little fishy that the Obama administration made Toyota recall 2.3 million vehicles while the government still owns GM?

@@

January 30th, 2010
2:19 pm

jay, it’s just that…

Oh never mind!

It stands to reason that a leftist, such as yourself, would wanna write columns that appeal to bloodsuckers. It’s your column.

larry

January 30th, 2010
2:30 pm

RW, does the fact that the defect killed more than 18 people and injured even more enter into the equation?

RW-(the original)

January 30th, 2010
2:30 pm

SeeBS is probably going to be shut down. They just showed Obama scrimmaging with the Georgetown basketball team. The Georgetown players backed away and let him drive in uncontested where Obama promptly blew the layup.

RW-(the original)

January 30th, 2010
2:32 pm

larry,

It certainly might. It might also be an over reach. Do you have any specifics to offer or just your usual bluster?

larry

January 30th, 2010
2:35 pm

Over reach? How many more people need to be killed? This should have been done a couple of months ago. I guess the government owns Ford, Nissan, etc, etc too.

RW-(the original)

January 30th, 2010
2:47 pm

larry,

The government doesn’t own Ford or Nissan. Was it really necessary to recall all the models they did? Now before you answer take a deep breath and try to understand it’s a real question.

TaxPayer

January 30th, 2010
2:55 pm

“The administration shares your belief that the current lack of a college football national championship playoff with respect to the highest division of college football … raises important questions affecting millions of fans, colleges and universities, players and other interested parties,” Weich wrote.

Weich made note of the fact that President Barack Obama, before he was sworn in, had stated his preference for a playoff system. In 2008, Obama said he was going to “to throw my weight around a little bit” to nudge college football toward a playoff system, a point that Hatch stressed when he urged Obama last fall to ask the department to investigate the BCS.

Talk about your bad blood. This has potential because it really connects with a lot of folks out there. I wouldn’t want to be on the wrong side of that table. In reality though, it’s most likely all about the money. Just imagine what a whole new series of ball games would do for revenues on everything from Cokes to wagers, friendly ones, that is.

TaxPayer

January 30th, 2010
2:57 pm

Oops, “Cokes to wagers” leaves out “beer” and that just won’t work.

larry

January 30th, 2010
3:00 pm

If all the models recalled used the same part from the same supplier, then yes ,it was necessary .

FrankLeeDarling

January 30th, 2010
3:02 pm

I see a whole new “bloody mary”on sundays

RW-(the original)

January 30th, 2010
3:03 pm

larry,

I got tired of waiting for you to do your research and did it for you

Wonder why we don’t hear jack about the GM vehicle in this recall…..

Jay

January 30th, 2010
3:05 pm

Your research also no doubt shows that Toyota is recalling those cars in China and Europe too, RW.

How does that fit into this little theory of yours?

stands for decibels

January 30th, 2010
3:11 pm

why we don’t hear jack about the GM vehicle in this recall….

http://online.wsj.com/article/BT-CO-20100129-717914.html?mod=WSJ_latestheadlines

RW-(the original)

January 30th, 2010
3:16 pm

Jay B,

What little theory of mine? Asking if anyone sees something as fishy hardly constitutes a theory and I do believe the research I linked shows it not to be an unnecessary recall.

Why are you so testy lately?

I Report (-: You Whine )-: mmm, mmmm, mmmmm!

January 30th, 2010
3:17 pm

I wonder how many sicko libs are scheming their neighbor’s children because of this column?

@@- It’s no use to appeal to their sense of decency, I don’t believe they have any, just sayin….

Jay

January 30th, 2010
3:18 pm

Oh, so you had no theory?

My mistake then….

stands for decibels

January 30th, 2010
3:19 pm

I wonder how many sicko libs are scheming their neighbor’s children because of this column?

If your blood alcohol level isn’t at or above .2%, Andy, you really ought to get some professional help at this point.

RW-(the original)

January 30th, 2010
3:20 pm

Well lookie here!!! sfb comes down on the side of it being what Jay B describes as my “little theory.” If the Vibe has the same gas pedal assembly and is safe then some of the Toyotas must be as well.

stands for decibels

January 30th, 2010
3:21 pm

But I kid. Seriously, I guess it’s a good thing those Fundies are such great breeders, huh?

RW-(the original)

January 30th, 2010
3:22 pm

Oh, so you had no theory?

Well Jay B, you should be able to point it out what with it being your blog and only 70 comments so far.

I Report (-: You Whine )-: mmm, mmmm, mmmmm!

January 30th, 2010
3:23 pm

But I kid. Seriously, I guess it’s a good thing those Fundies are such great breeders, huh?

Yes, STD, we give you good stock to attach yourself to.

I mean what good would it be to parasite off of some welfare queen, just sayin….

Jay

January 30th, 2010
3:24 pm

but … how could sfd come down on the side of something that doesn’t exist?

Now I’m really confused.

I Report (-: You Whine )-: mmm, mmmm, mmmmm!

January 30th, 2010
3:28 pm

I mean really, when you get right down to it, how much farther down the road is sucking blood out of the young when you consider the legislation currently being pushed by obozo?

stands for decibels

January 30th, 2010
3:28 pm

Yeah, I’m not sure which “side” I’m supposed to be on–I just was curious to see how many Vibes were out there. Not many. (figured that was the model that might be affected, since it’d been a joint venture with Toyota until recently.)

Jenifer

January 30th, 2010
3:31 pm

I Am Because They Are…Young, That Is

So, Madonna is, in essence, a vampire? Groovy.

http://www.vanityfair.com/online/culture/2009/06/12/she-is-because-they-are-young-that-is.html

RW-(the original)

January 30th, 2010
3:32 pm

Now I’m really confused.

That’s for sure. Maybe you should reread this sentence.

Well lookie here!!! sfb comes down on the side of it being what Jay B describes as my “little theory.”

You see, sfb is saying that the recall is likely not necessary and when I first posed that question you decided it was my “little theory” when it was only a question. Since you decided to read into it that I thought the recall was a ploy and named it a “little theory” there is now a way to come down on the side of what you describe as a “little theory” and sfb has provided the link.

See? Clear as the Hooch should be about now.

stands for decibels

January 30th, 2010
3:33 pm

sfb is saying that the recall is likely not necessary

but GM is recalling these vehicles.

[GM] said the Vibe was included in the Toyota recalls. “To the best of our knowledge, the Vibe vehicles were safely brought to a stop. We are investigating each of the claims,” the company added.

RW-(the original)

January 30th, 2010
3:34 pm

sfb,

The Vibe is the same car as the Toyota Matrix and they both use the same gas pedal assembly from the same vendor. Why is the Vibe safe to drive and the Matrix is not?

stands for decibels

January 30th, 2010
3:38 pm

Actually RW, I’m a little confused (I know, hard to believe, right)–the article doesn’t make it clear whether they are recalling the car or not.

I know if I had one I wouldn’t be in a big hurry to get it fixed, but that’s just me.

Jay

January 30th, 2010
3:40 pm

well, as SOMEBODY pointed out earlier, maybe it’s because GM is government owned.

Not that there’s a theory there or anything.

stands for decibels

January 30th, 2010
3:40 pm

Well, gotta run. Don’t leave your kids with any of them crazy blood-sucking liberals.

RW-(the original)

January 30th, 2010
3:43 pm

sfb,

I think the first five or six cars I ever owned it was more likely than not the accelerator would stick so it seems like an odd panic to me, but I guess there are lots of younger drivers that wouldn’t know what to do.

The Edmunds article I linked at 3:03 (although it could move to another time stamp if you hit refresh around here) is pretty comprehensive and it does list the Vibe as part of the recall.

md

January 30th, 2010
3:44 pm

Longer living populations? Fantastic news considering the planet’s resources are finite.

And why exactly did we bail out the auto industry vs all the other industries we didn’t help?

Jenifer

January 30th, 2010
3:45 pm

Obama Reprimands GOP: Stop Saying ‘This Guy’s Doing All Kinds Of Crazy Stuff…To Destroy America’

I doubt if this will have the intended effect of getting republicants to take a second look at the way they’re conducting this “debate”, but the President is at least exposing their dishonest rhetoric for what it is, and in a sensible way that ordinary Americans can understand IF THEY WISH TO.

http://thinkprogress.org/2010/01/29/obama-gop-retreat/

RW-(the original)

January 30th, 2010
3:45 pm

Jay B,

If it’ll put you in a better mood I’ll at least say that because I mentioned GM was government owned I can see why you jumped off the conspiratorial deep end. Better?

RW-(the original)

January 30th, 2010
3:46 pm

You’re welcome :-)

Jay

January 30th, 2010
3:47 pm

You put a smile on my face and a bounce in my step, RW. I thank you for that.

Jay

January 30th, 2010
3:47 pm

yeah, i alerted them to it, but .,..

RW-(the original)

January 30th, 2010
3:49 pm

Kewl! That space time continuum feature the IT ferrets put in here is some of their best work.

Jay

January 30th, 2010
3:50 pm

RW-(the original)

January 30th, 2010
3:52 pm

That’s hysterical.

/No telling where this’ll show up though so if it winds up under someone’s serious comment, my apologies.

Jenifer

January 30th, 2010
3:54 pm

Obama Calls Out GOP Hypocrisy For ‘Going To Ribbon Cuttings For The Same Projects That You Voted Against.’

When I see Eric Cantor I think “adolescent” every time. Obama lectured them and they replied with whining like they were 12 years old ‘but we have a bill.. geesh Obama!’ and he replies.. ‘well, I’ve read the bill.. it’s got no mechanism.’

It really is like he’s daddy Obama and they’re spoiled brats.

http://thinkprogress.org/2010/01/29/obama-ribbon-cutting/

md

January 30th, 2010
3:54 pm

TaxPayer

January 30th, 2010
3:57 pm

I have not personally looked into all the details regarding the Toyota recall but what little bit I did hear seemed to indicate that the vehicles included in the recall were those that could contain a “gas pedal” (note that this “gas pedal” is a little more complicated than the old mechanical linkage since it contains a position dependent feedback within the gas pedal housing) from a particular vendor (also note that more than one company manufactured the gas pedals and Toyota most likely did not have a database that identified each specific vehicle made with suspect gas pedal) that is suspected to “stick” and thus cause the driver to lose control over the vehicle’s acceleration.

Dusty

January 30th, 2010
3:57 pm

Well, I don’t have a Toyoto, just a lovely little American made Cavalier. My accelerator never sticks. But the next time I get a speeding ticket, I am ready!! Officer, MY ACCELERATOR GOT STUCK!! sniff…sob….sob

(RW, maybe Bookiman owns a Toyoto. That would make anybody a bit snippy at the moment.)

TaxPayer

January 30th, 2010
3:59 pm

md

January 30th, 2010
3:54 pm
3:51 test

Results indicate failure. Difference of 3 minutes. Please re-calibrate.

md

January 30th, 2010
3:59 pm

The pom pom business must be booming.

md

January 30th, 2010
3:59 pm

“Results indicate failure. Difference of 3 minutes. Please re-calibrate.”

The “test” initially posted behind RW, then later moved down one. Wonder how many posts I’ve not read since I don’t tend to go back up.