The Patriots exploded for three second-quarter touchdowns to take a 31-0 halftime lead behind more than 300 yards of total offense in the first two periods.
Cole Garvin threw for 215 yards and four scores, one of them a 68-yard strike to Kyle Wilson. Demarre Kitt had 117 receiving yards and two touchdowns, while Eric Swinney led the ground attack with 90 yards.
The Patriots led 10-0 in the first quarter on a Mitchell McMillin field goal and a 27-yard scoring run by Delvin Weems. Backup quarterback Trey Walker threw a 29-yard touchdown pass to Josh Branom on the final play of the third quarter, and Jayland Horne scored the final Sandy Creek touchdown with 6:16 to play in the game.
The Trojans got on the board late in the third on a 4-yard run by Quanderius Lee. It was the first time Banneker crossed midfield since its opening drive.